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  • 554 CRISPR tech selectively shreds cancer cells, including "undruggable" cancers (innovativegenomics.org)
    by gmays 7 hours ago | 149 comments
  • 208 I Am Not a Reverse Centaur (blog.miguelgrinberg.com)
    by ibobev 4 hours ago | 144 comments
  • 43 Swift at Apple: Migrating the TrueType Hinting Interpreter (swift.org)
    by DASD 2 hours ago | 18 comments
  • 156 How to setup a local coding agent on macOS (ikyle.me)
    by kkm 4 hours ago | 55 comments
  • 212 Malware developers added nuclear and biological weapons text to to their spyware (twitter.com)
    by marc__1 a day ago | 143 comments
  • 29 Mmorpg World of ClaudeCraft, vibe coded with Fable 5 (worldofclaudecraft.com)
    by beatthatflight an hour ago | 10 comments
  • 133 Pirates, a naval warfare game inspired by Sid Meier's Pirates (piwodlaiwo.github.io)
    by iweczek 5 hours ago | 62 comments
  • 46 Palantir loses legal challenge against Swiss investigative magazine (ft.com)
    by sschueller an hour ago | 6 comments
  • 144 Slightly reducing the sloppiness of AI generated front end (envs.net)
    by FergusArgyll 7 hours ago | 99 comments
  • 28 Launch HN: BitBoard (YC P25) – Analytics Workspace for Agents (bitboard.work)
    by arcb 5 hours ago | 15 comments
  • 9 Can I Buy Your KV Cache? (arxiv.org)
    by MediaSquirrel 2 hours ago | 7 comments
  • 88 Where Did Earth Get Its Oceans? Maybe It Made Them Itself (quantamagazine.org)
    by ibobev 6 hours ago | 51 comments
  • 63 Introduction to UEFI HTTP(s) Boot with QEMU/OVMF (blog.yadutaf.fr)
    by jtlebigot 7 hours ago | 20 comments
  • 22 Cosmodial Sky Atlas (killedbyapixel.github.io)
    by memalign 3 hours ago | 2 comments
  • 200 "Don't You Just Upload It to ChatGPT?" (correresmidestino.com)
    by speckx 4 hours ago | 182 comments
  • 102 A PDF that changes based on how its read (sgaud.com)
    by SarthakGaud 5 hours ago | 56 comments
  • 55 There Is Life Before Main in Rust (grack.com)
    by mmastrac a day ago | 13 comments
  • 122 Maxproof (arxiv.org)
    by ilreb 10 hours ago | 10 comments
  • 143 A dumpster arrived behind my university's library (yalereview.org)
    by mooreds 7 hours ago | 125 comments
  • 1443 If you are asking for human attention, demonstrate human effort (tombedor.dev)
    by jjfoooo4 a day ago | 452 comments
  • 33 You can power on a Mac remotely (jeffgeerling.com)
    by speckx 6 hours ago | 20 comments
  • Hazel (YC W24) Is Hiring a Full Stack Engineer (ycombinator.com)
    9 hours ago   job
  • 298 A Call to Action: Stop the FCC's KYC Regime (blog.lopp.net)
    by FergusArgyll 7 hours ago | 194 comments
  • 212 WASI 0.3 (bytecodealliance.org)
    by mavdol04 8 hours ago | 83 comments
  • 36 Show HN: StackScope – I crawled over 40k indie launches to see what they ship (stackscope.dev)
    by datafreak_ 6 hours ago | 12 comments
  • 43 EV demand up 50% in France and Germany since Iran war (reuters.com)
    by a_paddy 3 hours ago | 9 comments
  • 56 Encrypted Spaces An architecture for collaborative applications (encryptedspaces.org)
    by _____k 9 hours ago | 7 comments
  • 116 Looking Forward to Postgres 19: It's About Time (pgedge.com)
    by xngbuilds 5 hours ago | 33 comments
  • 154 A jacket that harvests drinking water from the air (news.utexas.edu)
    by ilreb a day ago | 96 comments
  • 10 Most Beautiful Will Ever Made (1936) (paperspast.natlib.govt.nz)
    by cf100clunk 4 hours ago | 2 comments