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  • 486 CRISPR tech selectively shreds cancer cells, including "undruggable" cancers (innovativegenomics.org)
    by gmays 6 hours ago | 132 comments
  • 170 I Am Not a Reverse Centaur (blog.miguelgrinberg.com)
    by ibobev 3 hours ago | 117 comments
  • 183 Malware developers added nuclear and biological weapons text to to their spyware (twitter.com)
    by marc__1 a day ago | 114 comments
  • 130 How to setup a local coding agent on macOS (ikyle.me)
    by kkm 3 hours ago | 44 comments
  • 111 Pirates, a naval warfare game inspired by Sid Meier's Pirates (piwodlaiwo.github.io)
    by iweczek 4 hours ago | 42 comments
  • 134 Slightly reducing the sloppiness of AI generated front end (envs.net)
    by FergusArgyll 6 hours ago | 93 comments
  • 83 Where Did Earth Get Its Oceans? Maybe It Made Them Itself (quantamagazine.org)
    by ibobev 5 hours ago | 49 comments
  • 24 Launch HN: BitBoard (YC P25) – Analytics Workspace for Agents (bitboard.work)
    by arcb 4 hours ago | 9 comments
  • 92 A PDF that changes based on how its read (sgaud.com)
    by SarthakGaud 4 hours ago | 51 comments
  • 138 A dumpster arrived behind my university's library (yalereview.org)
    by mooreds 6 hours ago | 115 comments
  • 1348 AI agent bankrupted their operator while trying to scan DN42 (lantian.pub)
    by xiaoyu2006 16 hours ago | 488 comments
  • 50 Introduction to UEFI HTTP(s) Boot with QEMU/OVMF (blog.yadutaf.fr)
    by jtlebigot 6 hours ago | 14 comments
  • 151 "Don't You Just Upload It to ChatGPT?" (correresmidestino.com)
    by speckx 3 hours ago | 125 comments
  • 48 There Is Life Before Main in Rust (grack.com)
    by mmastrac a day ago | 13 comments
  • 17 Cosmodial Sky Atlas (killedbyapixel.github.io)
    by memalign 2 hours ago | 1 comments
  • 66 Law Enforcement's "Warrior" Problem (2015) (harvardlawreview.org)
    by bookofjoe 4 hours ago | 48 comments
  • 119 Maxproof (arxiv.org)
    by ilreb 9 hours ago | 10 comments
  • 1420 If you are asking for human attention, demonstrate human effort (tombedor.dev)
    by jjfoooo4 a day ago | 446 comments
  • Hazel (YC W24) Is Hiring a Full Stack Engineer (ycombinator.com)
    8 hours ago   job
  • 32 Show HN: StackScope – I crawled over 40k indie launches to see what they ship (stackscope.dev)
    by datafreak_ 5 hours ago | 9 comments
  • 204 WASI 0.3 (bytecodealliance.org)
    by mavdol04 7 hours ago | 82 comments
  • 287 A Call to Action: Stop the FCC's KYC Regime (blog.lopp.net)
    by FergusArgyll 6 hours ago | 189 comments
  • 98 Looking Forward to Postgres 19: It's About Time (pgedge.com)
    by xngbuilds 4 hours ago | 30 comments
  • 71 New privacy frontier: Europe eyes crackdown on smart glasses (politico.com)
    by 1vuio0pswjnm7 4 hours ago | 54 comments
  • 50 Encrypted Spaces An architecture for collaborative applications (encryptedspaces.org)
    by _____k 8 hours ago | 5 comments
  • 152 A jacket that harvests drinking water from the air (news.utexas.edu)
    by ilreb a day ago | 96 comments
  • 372 Kimi K2.7-Code: open-source coding model with better token efficiency (huggingface.co)
    by nekofneko 10 hours ago | 197 comments
  • 17 You can power on a Mac remotely (jeffgeerling.com)
    by speckx 5 hours ago | 6 comments
  • 703 Nobody ever gets credit for fixing problems that never happened (2001) [pdf] (web.mit.edu)
    by sam_bristow 20 hours ago | 238 comments
  • 47 Show HN: Script to bulk delete Claude chats from the web UI (github.com)
    by ML0037 6 hours ago | 17 comments