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  • 70 Use of Bayesian methodology in clinical trials of drug and biological products [pdf] (fda.gov)
    by brendanashworth 5 days ago | 21 comments
  • 20 The relentless rule of my fitness tracker (timharford.com)
    by Arnt 2 days ago | 8 comments
  • 316 GitHub should charge everyone $1 more per month to fund open source (blog.greg.technology)
    by evakhoury 5 days ago | 341 comments
  • 72 Show HN: 1Code – Open-source Cursor-like UI for Claude Code (github.com)
    by Bunas 4 days ago | 48 comments
  • 90 Show HN: Gambit, an open-source agent harness for building reliable AI agents (github.com)
    by randall 4 days ago | 24 comments
  • 253 Raspberry Pi's New AI Hat Adds 8GB of RAM for Local LLMs (jeffgeerling.com)
    by ingve 4 days ago | 209 comments
  • 53 pf: Make af-to less magical (undeadly.org)
    by defrost 3 days ago | 15 comments
  • 30 Universal SSL exposes domains to BGP leaks (community.cloudflare.com)
    by 8organicbits 3 days ago | 1 comments
  • 268 Why senior engineers let bad projects fail (lalitm.com)
    by SupremumLimit 4 days ago | 162 comments
  • 7 The WebRacket language is a subset of Racket that compiles to WebAssembly (github.com)
    by mfru 2 days ago | discuss
  • 65 AV1 Image File Format Specification Gets an Upgrade with AVIF v1.2.0 (aomedia.org)
    by breve 2 days ago | 5 comments
  • 352 To those who fired or didn't hire tech writers because of AI (passo.uno)
    by theletterf 4 days ago | 264 comments
  • 6 Serpl – a pleasant TUI for regex and fixed-string search and replace (github.com)
    by Curiositry 2 days ago | discuss
  • 62 Launching the Handmade Software Foundation (handmade.network)
    by DeathArrow 2 days ago | 39 comments
  • 209 Data is the only moat (frontierai.substack.com)
    by cgwu 4 days ago | 47 comments
  • 36 When Sysadmins Ruled the Earth (2006) (craphound.com)
    by b112 a day ago | 2 comments
  • 186 JuiceFS is a distributed POSIX file system built on top of Redis and S3 (github.com)
    by tosh 4 days ago | 110 comments
  • 28 Building a Quake PC (fabiensanglard.net)
    by roskelld 3 days ago | 13 comments
  • 15 Ask HN: How to bullet proof yourself from AI? ()
    by max_ a day ago | 16 comments   ask
  • 37 We Gave Our Browser Agent a 3MB Data Warehouse (100x.bot)
    by shardullavekar 4 days ago | 5 comments
  • 126 Native ZFS VDEV for Object Storage (OpenZFS Summit) (zettalane.com)
    by suprasam 5 days ago | 31 comments
  • 27 Independent Guest Virtual Machine (IGVM) File Format (github.com)
    by ingve 4 days ago | 9 comments
  • 14 An explanation of cheating in Doom2 Deathmatch (1999) (doom2.net)
    by Lammy 2 days ago | 1 comments
  • 23 The Harvesting of Lettuce (sftw.substack.com)
    by HR01 a day ago | 3 comments
  • 42 Show HN: Hc: an agentless, multi-tenant shell history sink (github.com)
    by acarminati 3 days ago | 3 comments
  • 121 Edge of Emulation: Game Boy Sewing Machines (2020) (shonumi.github.io)
    by mosura 5 days ago | 8 comments
  • 25 Artisanal Code (sunnyamrat.com)
    by sunnyam 3 days ago | 7 comments
  • 281 Scaling long-running autonomous coding (cursor.com)
    by samwillis 5 days ago | 187 comments
  • 7 Fossgis 2026 – German language conference of FOSSGIS e.V. (OSGeo Local Chapter) (fossgis-konferenz.de)
    by slow_typist a day ago | discuss
  • 7 Why reinforcement learning plateaus without representation depth (NeurIPS 2025) (venturebeat.com)
    by brandonb 20 hours ago | 1 comments